CLACP (COL25A1) (NM_198721) Human Recombinant Protein-蛋白质/抗原/多肽-试剂-生物在线
安诺伦(北京)生物科技有限公司
CLACP (COL25A1) (NM_198721) Human Recombinant Protein

CLACP (COL25A1) (NM_198721) Human Recombinant Protein

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产品名称: CLACP (COL25A1) (NM_198721) Human Recombinant Protein

英文名称: CLACP (COL25A1) (NM_198721) Human Recombinant Protein

产品编号: PH30175E1

产品价格: 0

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围: null

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产品概述:Purified recombinant protein of Human collagen, type XXV, alpha 1 (COL25A1), transcript variant 1, Lys573-Gln653, with N-terminal His-ABP tag, expressed in E.coli, 50ug

蛋白长度:A DNA sequence encoding the region(Lys573-Gln653) of COL25A1

表达系统:E. coli

种属:Human

标签类型:N-His ABP

分子量:23.5 kDa

通用名:COL25A1

总结:This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

形式:Liquid

浓度:>50 ug/mL as determined by microplate BCA method

纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液:50mM Tris, pH8.0, 8M Urea

别名:AMY; CFEOM5; CLAC; CLAC-P; CLACP