重组人核纤层蛋白A
| 英文名称 | Recombinant human Lamin A/C protein, GST & His |
| 中文名称 | 重组人核纤层蛋白A |
| 别 名 | lamin A/C; LMN1; 70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; HGPS; IDC; LAMIN A; lamin A/C; LAMIN C; LDP1; LFP; LGMD1B; LMN 1; LMN A; LMN C; LMNA; LMNC; NY REN 32 antigen; PRO1; LMNA_HUMAN; Prelamin-A/C; Renal carcinoma antigen NY-REN-32; Recombinant human Lamin A/C protein, GST & His |
| 理论分子量 | 45kDa |
| 检测分子量 | 45 kDa |
| 性 状 | Liquid |
| 浓 度 | ＞0.5 mg/ml |
| 物 种 | Human |
| 序 列 | 26-198/664 |
| 纯 度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 活性 | Not tested |
| 标签 | GST & His |
| 缓 冲 液 | 20 mM Tris-HCl (pH=8.0) with 1 mM DTT, 1 mM EDTA and 10% Glycerol. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012] |
| 产品图片 |
 The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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